01
Adipose tissue sourcing & donor screening
RESEARCH & TECHNOLOGY
Research experience. Perspective for ingredient selection.
Knowledge from stem cell conditioned media research and commercialization informs plant-derived materials. Explore development backgrounds and ingredient-specific technical and quality documentation.
RESEARCH HERITAGE
Knowledge from conditioned media research. New directions in plant-derived materials.
Behind these materials is expertise accumulated through stem cell conditioned media research and commercialization. ABio materials carries that knowledge forward and combines it with its own plant research to develop today’s ingredients.
Technology development and documentation: ABio materials. EXOSOME supports ingredient selection and introduction to Japan.
01
STEM CELL CULTIVATION TECHNOLOGY
Celtivation™
ABio materials stem cell culture technology. We review cell origin, culture processes and conditioned media quality for each ingredient and provide corresponding materials and documentation.
02
Isolation of adipose-derived stem cells
03
Storage, thawing & large-scale culture
04
Production culture using Celtivation™
02
EXOSOME ISOLATION & PURIFICATION
ExoTraction®
ABio materials process technology for isolating and purifying exosomes from plants, lactic acid bacteria and other sources. Manufacturing and quality information is provided for the relevant material and application.
Smart Cultivating System
Plant & lactic acid bacteria culture systems
Isolation by Chemical
ATPS (Aqueous Two-Phase System) separation
High Purification
Large-scale production of high-purity plant-derived exosomes
PLANT-DERIVED PDRN
Developing plant-derived PDRN ingredients.
Based on ABio materials ingredient documentation, we present botanical origins, manufacturing processes, composition and specifications. Cosmetic ingredients and development for food use are covered separately.
03
HUMAN iPSC-DERIVED MESENCHYMAL STEM CELLS
iPSC-derived MSC
Research and culture technology presented by ABio materials for mesenchymal stem cells differentiated from iPSCs. Ingredient relevance and quality documentation are reviewed individually.
Uniformity
Aiming for more consistent cell quality than conventional MSCs
Scalability
Continuous, stable subculture and large-scale production
Safety
Review quality evaluations and test documentation for the material
Clean Facility
Documentation on the developer’s culture and manufacturing environment
04
MICROFLUIDIC LNP ENCAPSULATION
Cellularsome®
ABio materials encapsulation technology uses plant-derived phospholipids and microfluidic processing. It encapsulates ingredients in lipid bilayers and is presented separately from naturally derived exosomes.
Microfluidic Chip
Microfluidic processing designed for uniform particle formation
Plant Phospholipid
Bilayer structure using plant-derived phospholipids
LNP Encapsulation
Delivery design for encapsulating bioactive substances
Formulation
Product development solutions tailored to the material
TECHNICAL DOCUMENTS
Understand the material’s background. Make informed selections.
We organize information on origin, manufacturing, quality evaluation and test conditions. Assess ingredient studies and formulated-product studies according to their specific subjects and applications.
Technical information is presented using ABio materials public documentation. Contact EXOSOME for adoption requirements and availability.